![]() ![]() This release contains statements that constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Food and Drug Administration clearance prior to its introduction to the market. The device will provide the user with accessible and affordable real-time information on blood glucose levels. The first application of our Bio-RFID technology will be in a product marketed as a non-invasive glucose monitor. This patented and patent-pending technology makes it possible to effectively identify and monitor analytes that could only previously be performed by invasive and/or expensive and time-consuming lab-based tests. The Bio-RFID technology can be integrated into a variety of wearable, mobile or bench-top form factors. ![]() The Company refers to its technology as Bio-RFID™. is a public company whose shares trade on the NYSE American Exchange under the stock symbol “KNW.” The Company’s technology uses spectroscopy to direct electromagnetic energy through a substance or material to capture a unique molecular signature. This is a key component of realizing the Company’s vision for bringing an FDA-cleared product to the market.įor 2023, Know Labs remains focused on refinement and external validation of its technology and contributing to its growing body of peer-reviewed evidence, which can be found at About Know Labs, Inc. ![]() Gen 1 is expected to generate tens of billions of data observations to process which will be critical to helping validate algorithm performance across the real-world scenarios in which Know Labs’ glucose monitoring device may be used. To support this work, the Company is continuing to test with its Gen 1 device every day in parallel with ongoing clinical research with its stationary lab system. The Company’s focus is on collecting more high-quality, high-resolution data across a diverse participant population representing different glycemic ranges and testing scenarios, to refine its algorithms based on this new data, and to optimize its sensor in preparation for scale. Testing with the Gen 1 device is underway, optimizing the sensor configuration for data collection, including new environmental and human factors. ![]() In June 2023, Know Labs announced the completed build of its Gen 1 prototype, which incorporates the Bio-RFID sensor that Know Labs has been using to conduct clinical research in a lab environment for the last two years, and has published results of its proven stability, into a portable device. With this method, Know Labs was able to predict blood glucose in the test set – the dataset that provides a blind evaluation of model performance – with a MARD of 11.3%.Ĭomparatively, Know Labs released study results in May 2023 that analyzed data from five participants of a similar demographic using 1,555 observations from 130 hours of data collection, and the first application of the lightGBM ML model, which resulted in an overall MARD of 12.9%. In this new study where data collection was completed in May of 2023, Know Labs applied novel data preprocessing techniques and trained a Light Gradient-Boosting Machine (lightGBM) model to predict blood glucose values using 3,311 observations – or reference device values – from over 330 hours of data collected from 13 healthy participants. (NYSE American: KNW) today announced results from a new study titled, “ Novel data preprocessing techniques in an expanded dataset improve machine learning model accuracy for a non-invasive blood glucose monitor.” The study demonstrates that continued algorithm refinement and more high-quality data improved the accuracy of Know Labs’ proprietary Bio-RFID sensor technology, resulting in an overall Mean Absolute Relative Difference (MARD) of 11.3%.Īs with all Know Labs’ previous research, this study was designed to assess the ability of the Bio-RFID sensor to non-invasively and continuously quantify blood glucose, using the Dexcom G6® continuous glucose monitor (CGM) as a reference device. ![]()
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![]() ![]() Wondrich has his own history with shots-back in high school, he enjoyed something called The Snake Bite, which consisted of Yukon Jack Canadian whiskey and frozen lime juice. The Training Bra was “the color of Windex,” according to Wondrich, “and they would cost a quarter in pretty much any bar, so down the hatch it went.” This particular shooter is a delightful mix of white rum, triple sec or Cointreau, blue Curacao, and 7-Up, shaken and strained into a shot glass. Cutsail’s operation offered 170 different shooters, with classy names like the “Training Bra,” “The Fredneck,” “The Fat Rat’s Ass,” and “The Ganggreen.” It exists merely to confer a little cache on these pimpled baboons.”įast forward to 1991, when Larry “Cutty” Cutsail opened a bar in Frederick, MD called P.J. It has no particular attributes that would distinguish a good kamikaze from a bad one, like a dry martini or a tart gimlet. It’s a senseless, infuriating concoction made of equal parts vodka, lime juice, and triple sec…There are no standards for the kamikaze. ” is one of the classic disco cocktails invented by barbiturated teenagers. Heywood Gould, in his 1984 book Cocktail, writes, Here’s what he had to say about three of the infamous shots from the ’70s and ’80s:Īccording to Wondrich, the history of the shooter can be traced back to 1976, when the Kamikaze first appeared on the scene. “The market became flooded with new ideas for the first time in a long time, and old drinks were revised and remixed,” he said.īefore the event, we caught up with Wondrich to learn a bit more about the history of the shooter-that wonderful invention which we’re sure have been the cause of some of your best nights (and worst mornings). He pointed out that while the drinks being served at this time were “dumb and mostly awful,” the shift in cocktail culture was a positive development because, for the first time in decades, there was a period of cocktail creativity. Liquor companies started churning out sweet gimmick cocktails featuring fruit juices, dairy, and crazy names. Drugs made cocktails seem kind of tame, so they had to adapt by getting fancy and weird. Partially due to the rise of recreational drugs, alcohol itself was a less prevalent means of getting fucked up. Wondrich told the packed barroom, “By 1970, all the classic, well-made cocktails were considered old-fashioned and unpopular. Unsurprisingly, many consider the decades that followed to be the Dark Age of cocktails.Ĭocktail writer and historian David Wondrich ( Imbibe!, Punch) recently spoke about this ignominious period in cocktail history-and, more specifically, about the rise of the “shooter” (what we know today as the “shot”)-at Golden Cadillac in NYC’s East Village.ĭrugs made cocktails seem kind of tame, so they had to adapt by getting fancy and weird. The foxy lady was promoting the “Pink Squirrel” cocktail, a viscous concoction made with pink almond liqueur and creme de cacao. In the early ’50s, one liquor company hired a sexy female to walk into bars with a pink squirrel attached to a leash. Meanwhile, vodka became America’s spirit of choice. The late 1960s, ’70s, and ’80s were a bizarre and revolutionary time for cocktails.Ĭlassic, herbaceous liqueurs like Benedictine declined in popularity, while sickly-sweet flavored Schnapps surged in popularity. ![]() ![]() ![]() AOC Martinique is a set of production standards-like those used for bourbon and scotch-which helps deliver a consistent terroir. AOC Martinique Rhum Agricole Vieux is a generally expensive aged rum with a smooth character. The excellent Smuggler’s Cove cocktail book recommends an ounce-and-a-half of AOC Martinique Rhum Agricole Vieux combined with a half-ounce of blended aged rum. Recipes can be very specific about what rum bottles to use, though most recommend a combination of aged and dark rums, usually emphasizing the former. If you do like using a blender, most books recommend a flash blend poured with a gated finish. We’ve never felt like this method held us back, and if you are a slow sipper, it can yield a longer window before the drink becomes watery. We don’t like using blenders to make our cocktails, so instead we shake it to the moon and back over crushed ice, then strain the drink into another glass filled with more crushed ice. This drink, like many from its era, calls for a blender. As with most tiki fare, this cocktail makes an excellent summer sipper, but its strong allspice, vanilla, and clove elements give it a complexity that transcends season. ![]() Citrus is reduced to a secondary role here. This drink will reward lovers of tiki spice, as the double dose of falernum and allspice dram create a strong backbone that recurs through every step of the drink. Like most great tiki drinks, it engages the front of the tongue with citrusy flavors, before separating itself from the pack with a deeply transfixing wash of rum and clove. With joyous whiffs of cherry, clove, vanilla and buttery sugarcane, this drink smells like a magical tiki explosion. This makes it instantly recognizable to those in the know, though folks outside the know also rejoice, because hey look three tasty cherries. The name means “V” (for victory) in Morse code, and the trademark three-cherry garnish symbolizes the aforementioned dots. Originally created at the end of World War II by Tiki grand-pappy Don the Beachcomber, and lovingly revitalized by Beachbum Berry in his book Sippin’ Safari the three dots & a dash cocktail is fundamentally and undeniably tiki. ![]() ![]() Drain the water, and put it in a clean bowl.The herbs are left to soak in boiling water until it cools.Put the herbs in a glass container, then pour boiling water over them.Half a tablespoon of dried thyme, or a tablespoon of fresh thyme leaves.Half a tablespoon of dried rosemary, or a tablespoon of fresh rosemary leaves.Maintaining smoothness of hair: This method is used to darken and soften hair color, in addition to maintaining the health of the scalp, and the method is:.Strain the water from thyme, and use it to rinse the hair.Intensification and growth of hair: Thyme water can be used to regrow hair, and this can be done by mixing thyme oil with a carrier oil, or by using thyme water, and the method is:.Thyme is a herb rich in potassium, magnesium and selenium, so it can stimulate hair follicles, which leads to hair growth, in addition to that it contains antiseptic and anti- fungal properties that maintain the health of the scalp, and methods of use are: Thyme contains benefits for hair, including: ![]() Thyme herb lasting aromatic evergreen of the family of the mint, which is known in many parts of the world since ancient times, and is used thyme in cooking and has many medical benefits, and used by the Babylonians, Assyrians and Sumerians ancient since 5000 years in medical treatments, recommended by Hippocrates aka Abu Western medicine in the year 370 BC in the treatment of respiratory diseases. ![]() ![]() ![]() Unless you’re a monk or the King of Thailand, not returning someone’s respectful wai is impolite. Saying hello in Thai is often accompanied with a wai - the famous, prayer-like gesture with palms together and head slightly bowed. Sawasdee can even for “goodbye” if you choose. You can use sawasdee for people both older and younger than yourself. Honorifics don't affect the greeting, either. Unlike when saying hello in Malaysia and Indonesia, the time of day does not matter when greeting people in Thai. How are you?: sabai dee mai (sounds like “sah-bye-dee my?”).Hello: sawasdee (sounds like “sah-wah-dee krap / kah”).The default way to say hello in Thai is with a friendly sawasdee khrap (if you are male) or sawasdee kha (if you are female). It can also be a high tone for emphasis.ĭon’t worry: after a week or so in Thailand, you’ll find yourself reflexively saying khrap or kha without even / Getty Images Kha (sounds like “khaaa”): Women say kha with a drawn-out, falling tone.Yes, it inconveniently sounds like “crap!” - although, the r is often omitted in Thai, making khrap! sound more like kap! Khrap (sounds like “krap!”): Male speakers say khrap sharply with a high tone for emphasis.For instance, if you tell a Thai woman thank you, she may reply with an enthusiastic “ khaaaa.” At the end of a transaction, a man may say "khrap!" indicating both thanks and that "we are done here." Khrap and kha are also used standalone to indicate agreement, comprehension, or acknowledgement. Depending on the gender of the speaker (men say khrap women say kha), they are added to the end of a statement to indicate respect. Without question, the two words you’ll hear the most often on a trip to Thailand are khrap and kha. ![]() The word "Thai" isn't pronounced "thigh," it's Thai! For instance, Phuket - one of the most popular islands in Thailand - is pronounced “poo-ket.” The letter r is often omitted or spoken as an L in Thailand.Transliterations of these popular expressions for traveling in Thailand differ, but English-equivalent pronunciations are provided below. Usually.Īlong with five tones, the Thai language also has its own unique script. Fortunately, context will usually help people understand you. Words take on different meanings depending upon which of the five tones are used. There is one small catch: Thai is a tonal language. Yes, learning a little Thai is optional, but speaking a few words of the local language can lead to some fun cultural interactions! Although the language barrier isn't much of a problem while traveling in Thailand, knowing a few useful phrases in Thai will really enhance your experience there. ![]() |
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